April 24th, 2014

saxifraga-x-urbium:

bottle-of-smoke:

lazyscience:

somethingkindofstrange:

j-e-r-a:

microraptoria:

Source. This is a real thing. It’s happening.

HIV Has Been Cured in a Child for the First Time

HIV Cure: New Drug ‘Vacc-4x’ May Become First Functional Cure Against the Virus

The Man Who Had HIV and Now Does Not

This is HUGE news, and of course no one is talking about it because it is not a part of popular culture. For the first time in the history of the world, there is a possible preventative cure for one of the most deadliest viral diseases to have entered the human gene pool. There is hope for those who have been diagnosed with a disease that may have given them only 20 or so years to live. This breakthrough in the science/pharmaceutical community means that other viral diseases and genetic mutations that were once incurable are now on the table for complete eradication. I’m absolutely seething that no one is talking about this on the news 24/7, but instead talking about Miley Cyrus or the biggest videos on Vine.

Okay, so, I don’t want to discourage anyone from hope or minimize the efforts of these researchers - but so far all of these treatments 1) have not yet produced reproducible/consistent results - we don’t know what patients will respond and which will not,  2) hugely expensive - the baby was treated with a much higher than normal dose of existing antiretroviral drugs, wholesaling for thousands of dollars a month and Vacc-4,  IF they can determine which patients will respond well I cannot think will be any cheaper, especially while under patent and allogeneic stem cell transplant costs between $500K and $1M US because the patient’s immune system is totally destroyed by chemotherapy drugs and/or irradiation so they need to be hospitalized in protective isolation and receive a high amount of care while this is happening 3) carry a not inconsiderable risk of death (around 25 percent for allogeneic stem cell transplant) or permanent autoimmune/other health problems like graft versus host disease, sterility, and increased risks of certain cancers depending on the preparative regimen for stem cell transplant, multiple sclerosis for the drug in the second link, and a laundry list of liver, kidney and heart disease and/or even permanently changing the appearance of your face and body for standard antiretroviral therapy - we have no idea what kind of late effects might show up for the child who recieved that treatment, there may be none, there could potentially be serious ones—does it help to cure HIV if it means that ten years down the road she’ll have Hodgkin’s disease or acute leukemia, or liver failure? What I can say for sure is that it will be YEARS before any of these treatments are offered outside of carefully regulated studies to improve the chances of the treatment doing more good than harm - antiretroviral therapy is not one of my areas of expertise, but  I CAN tell you that other HIV positive patients have undergone stem cell transplant and not had the same curative effect as the gentleman in the third link. 

Believe me, when there is a CURE, as opposed to hopeful developments that may or may not pan out, it will be big news. Huge.

 Reblogging for the last comment. While there’s no doubt that the media has a frustrating focus sometimes, the fact of the matter is that neither of these can be considered “cures”, at least right now. The Berlin patient in particular - do people not realise what a bag of dicks a bone marrow transplant is? An HIV positive person with access to HAART can live a more or less normal life with a more or less normal lifespan (providing they stick to the regimen), and while the prognosis for patients receiving a bone marrow transplant is improving it is still a dangerous procedure with high morbidity and mortality. My job involves monitoring both HIV patients and bone marrow transplant recipients and honestly given the choice? I think I’d rather be in the first group.

plz listen to the science lady

(Source: itstonybetch, via cowboybebopandhiscomputer)

April 23rd, 2014

tsuntsundio-kun:

Jotaro Kujo (Black Version), Re-release.

Super Figure Art Collection.

Medicos.  ¥6800.  September 2014.

(Source: amiami.com, via starcissus)

spookylikefox:

[crashes 1920s Bentley through ur wall] READ GOOD OMENS

(via tashaclint)

THE SURVIVORS OF THE ORIGINAL TEAM ATLANTA.

(Source: clumsycarl, via killsandthrills)

missdontcare-x:

RDJ’s chair tho..

(via killsandthrills)

mangneto:

when will i stop drawing cats

mangneto:

when will i stop drawing cats

(via skeletonspookies)

miaouler:

{Δ} : because how could i not draw this guy?

miaouler:

{Δ} : because how could i not draw this guy?

(via skeletonspookies)

captainhanni:

sighs @ own self

darklordflareon:

he died a hero’s death

darklordflareon:

he died a hero’s death

(via skeletonspookies)

thephotogfeminist:

"Losing your Virginity" will henceforth be called "your sexual debut."

Because you’re not fucking losing anything.

(via ecstasydragon)

(Source: latteveria, via boothrat)

(Source: dreamyindemeanour, via lusilly)